Methylene chloride
75-09-2
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Solvent is the primary application of Dichloromethane. With strong dissolving capacity, low boiling point, relatively low toxicity and excellent reaction inertness, Dichloromethane has become the most frequently used organic solvent in organic synthesis, with a status almost equivalent to that of water in inorganic salt chemistry. It is widely used in the production of safety motion picture films and polycarbonate, and the rest is used as coating solvent, metal degreaser, aerosol spray, polyurethane foaming agent, release agent and paint remover. In the pharmaceutical industry, it is used as a reaction medium for the preparation of ampicillin, carbenicillin, cephalosporin, etc. It is also used as a solvent in film production, petroleum dewaxing solvent, aerosol propellant, extractant for organic synthesis, foaming agent for the production of polyurethane and other foamed plastics, and metal cleaning agent. Dichloromethane is inert due to stereoelectronic effects and usually does not participate in chemical reactions, but it can react under certain conditions. There have been industrial accidents where residual Dichloromethane reacted with sodium azide in N,N-Dimethylformamide to generate diazidomethane, causing factory explosions. In China, Dichloromethane is mainly used in the film production and pharmaceutical industries, with film production accounting for 50% of total consumption, pharmaceuticals 20%, cleaning agents and chemical industry 20%, and other applications 10%.
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